1.1 History
1981 |
Discovered as an epidermal cell-derived thymocyte-activating factor (NIH, USA) |
1986 |
Found in normal human epidermis (University Hospital, Geneva, Switzerland) |
1988 |
Identified as a regulator of the turnover of extracellular matrix components of the dermis, e.g. collagen, elastin, hyaluronic acid (Universities of California and of Tennessee) |
1998 |
Identified as a primary inductor of epidermis renewal (Research institutions in Heidelberg and Zurich) |
2002 |
Identified as a factor responsible for normal skin barrier function (University of California) |
Age related DERMATOPOIETIN® deficit
DERMATOPOIETIN® is continuously produced in upper layer of epidermis throughout our life. An important fact is that constitutive production of DERMATOPOIETIN® in skin drastically falls with aging. Thus the deficit in production and activity both lead to skin renewal failure. Skin tissue misbalance associated with age-related deficits of DERMATOPOIETIN® can be successfully solved using DERMATOPOIETIN® prepared biotechnologically.
