DERMATOPOIETIN® is the body's own regulator of tissue renewal. The natural production of DERMATOPOIETIN® in the skin decreases with age causing most of the signs of skin aging. The regular cosmetic application of DERMATOPOIETIN® provides the full compensation for the deficit and consequently enhances skin renewal.

DERMATOPOIETIN® is a vital player that orchestrates entire process of skin renewal via initiation of a cascade of paracrine regulators, activation of proliferation of keratinocytes and fibroblasts, and regulates synthesis/degradation of extracellular matrix components. Under aging both the production and response to DERMATOPOIETIN® in skin are drastically reduced leading to disturbed skin renewal process and weak skin barrier function. It is well-documented that any mismatches arising from age-related deficits of DERMATOPOIETIN® can be successfully solved using its biotechnological equivalent. This provides a strong scientific base for the use of DERMATOPOIETIN® in anti-aging cosmeceutical products.

DERMATOPOIETIN® is a 159 amino acid long polypeptide. It is constantly produced by skin almost exclusively onto the stratum corneum (upper skin layer) of the human epidermis. DERMATOPOIETIN® serves as an autocrine factor that initiates a cascade of events directed to deeper layers of skin. It activates expression of growth and differentiation factors that initiate cellular proliferation and migration events leading to tissue renewal. Since its discovery in early 1980s, this agent has undergone extensive scientific research worldwide:

1.1 History

1.2 How it works?

1.3 Safety

1.4 Efficacy

1.5 Hexapeptide 18