Raw Materials

Dermatopoietin® is our trade name for human interleukin-1 alpha (IL-1 alpha). Dermatopoietin® is an epidermal cytokine produced in healthy skin on a constitutive basis by keratinocytes. It acts as key regulator of skin renewal and hair growth.

Dermatopoietin® is a 159 amino acid polypeptide. For application in cosmetic products it is produced by recombinant technology. Due to its size Dermatopoietin® does not penetrate the skin. Contact with the first living layer of epidermal cells in the outer skin trigers a cascade of reactions which result in restructuring the dermis (inner layer of skin), rebuilding the collagen/elastin network, and controlling the hair cycle. For a detailed description of its mechanism of action please visit the Scientific Portal.

The efficiency profile of Dermatopoietin® as active ingredient in cosmetic preparations include a strong

• anti-aging effect (increase of skin elasticity and skin thickness, reduction of wrinkles)
• anti-cellulite effect (smoothening of skin)
• reduction of hair loss, increase of hair growth

For optimal cosmetic effect application of products containing Dermatopoietin®alternate with cosmetic products without Dermatopoietin®. The active treatment phase with Dermatopoietin® lasts from four days (anti-hair loss) up to four weeks (skin care) and is followed by application of a maintenance product for a defined period as described for each product. This dual-phase application mode of alternate treatment and maintenance phases is related to the mechanism of action of Dermatopoietin which involves complex biological regulation loops subject to distinct time and dose regimens.

has applied a series of patents for application of IL-1 alpha in cosmetics and dermatology.

Material Safety Data Sheet